Abstract: When conducting oil and gas exploration in the Pre-Mesozoic in the northern part of the Eerduos Basin, it should be borne in mind that the basin was once a continental margin. Based on the structural setting in the different stages of tectonic movement, the author divides the region into five structural units from west to east as follows: the Helan fold zone, the Tianhuan syclinal zone, the hinge zone, the monoclinal zone and the Wula nger uplift. When exploring for oil and gas in the northern part of the basin, the following points should be given proper attention: 1) from Zhuzishan to Majiatan, keep an eye on the structure there which is a hinge zone from a slope leading to a deep trough, and from Shanyanjing to Bujianghai fault-depression zone, on the hidden unconfo rmity surface at the bottom of the upper and lower Paleozoic and the Shihezi formation; 2) notice the uplift of the lower Paleozoic from Qingyang to Wushenqi and also the middle section of the Helan fold zone; 3) the possibility of Wulanger uplift being a petroliferous buried hill.